Urticaria or hives is an allergic condition characterized by itchy, red, raised patches on skin. These patches disappear in a few hours but reappear at the same or a new area. Generally, Urticaria can be easily treated and doesn't cause much trouble to the person but in some cases it can get severe and chronic if it takes more than 6 weeks. Urticaria can be a manifestation of many conditions and illnesses, rather than one illness. The effectiveness of treatment depends on the diagnostic expertise, experience and attention they extend towards you.
Mast cell degranulation is the mechanism behind hives. If we put it in simple words, some white blood cells go berserk and cause the dismissal of histamine. And in response to, antigens (intruders, real or seeming) which may come into contact through touch, breathing or digestions, the Mast cells fire back to resist them. There can be various reasons that your body produces antigens including factors like thyroid or lupus, inflammation or cancer like chronic diseases.
There are little receptors for immunoglobulin e antibody (IgE) on the surface of the Mast Cells and these stick to any antigens that come into the contact with your body. When the mast cell gets loaded it starts firing its weapons and it encourages other mast cells as well as other inflammatory cells to fire also. As the mast cells fire, they release histamine. Blood vessels seep out fluid due to vasodilation (where the capillaries increase in diameter) into the surrounding tissues by histamine and other mast cell by-products. The production of Hives occurs as a result of the infusion of histamine.
If you have frequent episodes of Urticaria, here are some tips suggested by Dr. Nivedita Dadu for Urticaria treatment in Delhi at Dadu Medical Centre located in Delhi, Vasant Vihar (South Delhi), Rajouri Garden (West Delhi), the most preferred dermatologist in Rajouri Garden.
If you've experienced any of these, you may indeed have autoimmune Urticaria, and this warrants further investigation.
What's new in Urticaria treatment?
BIOLOGICALS -- Monoclonal antibody to IgE is a recombinant biologic molecule effective for chronic Urticaria is currently F.D.A. approved for treatment of chronic Urticaria. It is given as injections, to adults and children above 12 yrs of age.
If you have tried a lot of treatment and are still not relieved of the symptoms, we suggest you book an appointment with Dr. Nivedita Dadu and we will be happy to help you.
Kanika - Monday, 16 April 2018
V nice doctor thx so much doctor
✱ Results may vary person to person.